学习经历
2017年5月，理学博士，新加坡南洋理工大学 (导师：Prof. Robin Chi)
2010年6月，理学硕士，上海大学&上海有机所联合培养 (导师：曹卫国教授&赵刚研究员)
2007年7月，理学学士，曲阜师范大学，化学与化工学院
工作经历
2019年10月--至今，太阳集团城娱8722，教授
2016年12月--2019年10月，新加坡南洋理工大学，博士后研究员(Research Fellow)
2010年8月--2012年12月，新加坡南洋理工大学，研究助理 (Research Assistant)
研究方向
基于有机小分子催化的绿色有机合成；手性药物驱动的不对称有机合成；有机不对称催化方法学研究
(欢迎博士后、研究助理以及研究生的加入；欢迎对有机合成化学感兴趣的员工加盟一起学习和探索，具有有从事机合成、有机催化经验者优先)
主要论文
24. Hongling Wang,Yuhuang Wang, Xingkuang Chen, Chengli Mou, Lutan Pan, Zhichao Jin, and Yonggui Robin Chi*, Chiral Nitroarenes as Enantioselective Single-Electron-Transfer Oxidants for Carbene-Catalyzed Radial Reactions, Org. Lett., 2019, 21, 7440-7444. (IF = 6.555)
23. Ruoyan Huang,▮Xingkuan Chen,▮ Chengli Mou, Guoyong Luo, Yongjia Li, Xiangyang Li, Wei Xue, Zhichao Jin, Yonggui Robin Chi*, Carbene-Catalyzed α-Carbon Amination of Chloroaldehydes for Enantioselective Access to Dihydroquinoxaline Derivatives, Org. Lett., 2019, 21, 4340-4344. (IF = 6.555) (▮equal to first author)
22.Xingkuan Chen, Hongling Wang, Kazuki Doitomi, Chong Yih Ooi, Pengchang Zheng, Song Yang, Bao-An Song, Hajime Hirao, Yonggui Robin Chi*, A Reaction Mode of Carbene-Catalysed Aryl Aldehyde Activation and Induced OH Functionalization, Nat. Commun. 2017, 8, 15598. (Highlighted by Synfacts) (IF = 11.878, Citation: 2)
21.Xingkuan Chen, Jacqueline Zi Mei Fong, Jianfeng Xu, Chengli Mou, Yunpeng Lu, Song Yang, Bao-An Song, and Yonggui Robin Chi*, Carbene-Catalyzed Dynamic Kinetic Resolution of Carboxylic Esters, J. Am. Chem. Soc., 2016, 138, 7212-7215. (one of the most read JACS articles in May 2016). (IF = 14.695, Citation: 9)
|
20. Jianfeng Xu,▮Xingkuan Chen,▮Song Yang, Yonggui Robin Chi*,Aminomethylation of Enals through Carbene and Acid Cooperative Catalysis: Concise Access to b2-Amino Acids, Angew. Chem., Int. Ed., 2015, 54, 5161-5165. (▮equal to first author), (Highlighted by Synfacts) (IF = 12.257, Citation: 27).
19.Xingkuan Chen, Song Yang, Bao-An Song, Yonggui Robin Chi*,Functionalization of Benzylic C(sp3)-H Bonds of Heteroaryl Aldehydes through N-Heterocyclic Carbene Organocatalysis, Angew. Chem. Int. Ed., 2013, 52, 11134-11137. (IF = 12.257, Citation: 55).
18. Junming Mo,▮Xingkuan Chen,▮ Yonggui Robin Chi*, Oxidative γ-Addition of Enals to Trifluoromethyl Ketones: Enantioselectivity Control via Lewis Acid/N-Heterocyclic Carbene Cooperative Catalysis, J. Am. Chem. Soc., 2012, 134, 8810–8813.(▮equal to first author, highlighted in JACS Spotlights, hot paper), (IF = 14.695, Citation: 213)
17.Xingkuan Chen, Xinqiang Fang, Bhoopendra Tiwari, Yonggui Robin Chi*, Cis-Enals in N-Heterocyclic Carbene-Catalyzed Reactions: Distinct Stereo-Selectivity and Reactivity, Chem. Sci., 2013, 4, 2613-2618. (IF = 9.556, Citation: 35).
16.Xingkuan Chen, Runjiang Song, Yingguo Liu, Chong Yih Ooi, Zhichao Jin, Tingshun Zhu, Lin Hao, Hongling Wang, Yonggui Robin Chi*, Carbene and Acid Cooperative Catalytic Reactions of Aldehydes and o-Hydroxybenzhydryl Amines for Highly Enantioselective Access to Dihydrocoumarins, Org. Lett., 2017, 19, 5892-5895. (IF = 6.555).
15. Hongling Wang,▮Xingkuan Chen,▮ Yongjia Li, Jilan Wang, Shuquan Wu, Wei Xue, Song Yang,* Yonggui Robin Chi*, Addition of N-Heterocyclic Carbene Catalyst to Aryl Esters Induces Remote C-Si Bond Activation and Benzylic Carbon Functionalization. Org. Lett., 2018, 20, 333-336. (IF = 6.555) (▮equal to first author)
14.Xingkuan Chen, Chang-Wu Zheng,Gang Zhao*, Wei-Guo Cao*，Highly Enantioselective Michael Addition of Cyclic 1,3-Dicarbonyl Compounds to β, γ-Unsaturated -Keto Esters. Adv. Synth. Catal., 2010, 352, 1648–1652. (IF = 5.451, Citation: 49)
13. Lin Hao,▮Xingkuan Chen,▮ Yonggui Robin Chi*, Facile Acess to Pyridines via DMAP –Mediated Reactions of a-Chloro Acetic Esters and Unsaturated Imines, Org. Chem. Front., 2014, 1, 148-150. (▮equal to first author), invited paper (IF = 5.076, Citation: 8)
12. Yingguo Liu, Qiao Chen, Chengli Mou, Lutai Pan, Xiaoyong Duan, Xingkuan Chen, Hongzhong Chen, Yanli Zhao , Yunpeng Lu, Zhichao Jin & Yonggui Robin Chi*, Catalytic Asymmetric Acetalization of Carboxylic Acids for Access to Ahiral Phthalidyl Ester Prodrugs. Nat. Commun. 2019, 10, 1675. (IF = 11.878)
11. Xinqiang Fang, Xingkuan Chen, Hui Lv, Yonggui Robin Chi*, Enantioselective Stetter Reactions of Enals and Modified Chalcones Catalyzed by N-Heterocyclic Carbenes, Angew. Chem. Int. Ed., 2011, 50, 11782-11785. (IF = 12.257, Citation: 69).
10. Wendy Wen Yi Leong, Xingkuan Chen, Yonggui Robin Chi*,NHC-catalyzed Reactions of Enals with Water as a Solvent, GreenChem. 2013, 15, 1505-1508. (IF = 9.405, Citation: 18).
9.Qiang Tang, Xingkuan Chen, Bhoonpendra Tiwari, Yonggui Robin Chi*, Addition of Indoles to Oxyallyl Cations for Facial Access to α-Indole Carbonyl Compounds,Org. Lett., 2012, 14,1922-1925.(IF = 6.555, Citation: 28).
8.Xinqiang Fang, Xingkuan Chen, Yonggui Robin Chi*, Enantioselective Diels–Alder Reactions of Enals and Alkylidene Diketones Catalyzed by N-Heterocyclic Carbenes, Org. Lett., 2011, 13, 4708–4711. (IF = 6.555, Citation: 74)
7. Ying-Quan Yang, Xingkuan Chen, Gang Zhao*, Organocatalyzed Enantioselective Michael Additions of nitroalkanes to Enones by Using Primary–Secondary Diamine Catalysts. Chem. Commun., 2010, 46, 4130–4132. (IF = 6.164, Citation: 30)
6. Junming Mo, Ruojie Yang, Xingkuan Chen, Bhoopendra Tiwari, Yonggui Robin Chi*,Direct α‑Functionalization of Simple Aldehydes via Oxidative N‑Heterocyclic Carbene Catalysis, Org. Lett., 2013, 15, 50-53. (IF = 6.555, Citation: 45).
5.Lin Hao, Yu Du, Hui Lv, Xingkuan Chen, Huishen Jiang, Yaling Shao, Yonggui Robin Chi*, Enantioselective Activation of Stable Carboxylate Esters as Enolate Equivalents via N-Heterocyclic Carbene Catalysts, Org. Lett., 2012, 14, 2154–2157. (IF = 6.555, Citation: 105)
4.Junmin Zhang, Bhoopendra Tiwari, Chong Xing, Xingkuan Chen, Yonggui Robin Chi*, Enantioselective Oxidative Cross-Dehydrogenative Coupling of Tertiary Amines to Aldehydes, Angew. Chem. Int. Ed., 2012, 51, 3649-3652. (Highlighted by Synfacts), (IF = 12.257, Citation: 98).
3.Wen Liu, Jing Zhou, Changwu Zheng, Xingkuan Chen, Hua Xiao, Yingquan Yang, Gang Zhao*, Tandem Cross-Rauhute-Currier/Cyclization Reactions of Activated Alkenes to Give Densely Functionalized 3,4-Dihydropyrans. Tetrahedron2011, 67, 1768-1773. (IF = 2.651, Citation: 20)
2. Chang-Wu Zheng, Ying-Peng Lu, Jun-Kang Zhang, Xingkuan Chen, Wen-Ying Ma, Gang Zhao*, Enantioselective 4-benzyloxy Prolinol-Catalyzed Diels–Alder Reaction: An Efficient Route to Functionalized Tetrahydrocarbazoles. Chem. Eur. J., 2010,16, 5853–5857. (IF = 5.160, Citation: 92)
1.Ying-Quan Yang, Zhuo Chai, Hai-Feng Wang, Xingkuan Chen, Hai-Feng Cui, Chang-Wu Zheng, Gang Zhao*; Chiral Primary–Secondary Diamines Catalyzed Michael-Aldol-Dehydration: Highly Enantioselective Synthesis of Functionalized Chiral Cyclohexenones. Chem. Eur. J.,2009, 15, 13295-13298. (IF = 5.160, Citation: 39)
著作章节：
1. Zhichao Jin, Xingkuan Chen and Yonggui Robin Chi*N-Heterocyclic Carbenes in Organocatalysis, 2019, 187-210, Wiley-VCH Verlag GmbH & Co. KGaA, ISBN: 978-3-527-34310-2.
讲授课程
有机化学，有机化学实验
荣誉与奖励
2019 新加坡化学会早期职业奖（SNIC-Prof Lee Soo Ying Early Career Research Award）
2018 “海外高层次人才项目”入围答辩候选人
2016 中国留学基金委--国家优秀自费职工奖
2014 新加坡南洋理工大学博士研究生全额奖
2010 上海大学“陈念贻”教授一等奖
